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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T78259 Anti-Mouse CD8 beta Antibody (53-5.8)

Anti-Mouse CD8 beta Antibody是一种源自大鼠的IgG1类免疫抑制性抗体,专门针对小鼠的CD8 beta分子。
T40132 Insulin β Chain Peptide (15-23)

Insulin β Chain Peptide (15-23), also referred to as INS, is an insulin-derived peptide that is specifically recognized by islet-associated T cells. The tetramer of Insulin β Chain Peptide (15-23) effectively stained the INS-reactive CTL clone G9C8; however, neither this tetramer nor the negative control tetramer (TUM) exhibited staining on the splenic CD8+ T cells obtained from NOD or 8.3-TCRαβ transgenic NOD mice.
T83779 EP4 Antagonist 14

Prostaglandin E2 Receptor 4 Antagonist 14,PGE2 Receptor 4 Antagonist 14

EP4 antagonist 14是一种前列腺素E2(PGE2)受体亚型EP4的拮抗剂,其在使用表达人源受体的HEK293细胞的报告基因测定中的IC50值为1.1 nM。它还能抑制PGE2诱导的同种细胞中的β-阿雷斯汀招募(IC50 = 0.9 nM)。EP4 antagonist 14(10 µM)能减少RAW 264.7巨噬细胞中PGE2诱导的mRNA表达,这些mRNA编码Il-4、巨噬细胞甘露糖受体1(Mrc1)、几丁质酶样蛋白3(Chil3)、趋化因子(C-X-C)基序配体1(Cxcl1)、表达在髓样细胞上的触发受体2(Trem2)和精氨酸酶-1(Arg1)。在体内,EP4 antagonist 14(每天30 mg/kg),结合抗PD-1抗体,能够在CT26小鼠结肠癌模型中抑制肿瘤生长并增加CD8+ T细胞对肿瘤的浸润。

化合物

Anti-Mouse CD8 beta Antibody (53-5.8)
Cat.No: T78259
Synonym:
Target:
Insulin β Chain Peptide (15-23)
Cat.No: T40132
Synonym:
Target:
EP4 Antagonist 14
Cat.No: T83779
Synonym: Prostaglandin E2 Receptor 4 Antagonist 14,PGE2 Receptor 4 Antagonist 14
Target:
Cat. No. Product Name Species Expression System
TMPY-04925 CD8 beta Protein, Human, Recombinant, Biotinylated

LY3,LYT3,CD8b molecule,P37,LEU2,CD

Human HEK293 Cells
CD8 beta Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.
TMPY-06256 CD8 beta Protein, Cynomolgus, Recombinant (hFc)

CD8 β,CD8b mole...

Cynomolgus HEK293 Cells
CD8 beta Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.88 kDa and the accession number is XP_005575417.1.
TMPJ-00092 CD8 beta Protein, Human, Recombinant (His)

T-Cell Surface Glycoprotein CD8 Beta Chain...

Human HEK293 Cells
T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha a...
TMPY-02925 CD8 beta Protein, Human, Recombinant

LEU2,P37,CD8b molecule,LYT3,CD

Human HEK293 Cells
CD8 beta Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is P10966-1.
TMPY-05350 CD8 alpha Protein, Cynomolgus, Recombinant (hFc)

CD8 α,CD8a molecule

Cynomolgus HEK293 Cells
CD8 alpha Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession number is XP_005575419.1.
TMPY-02703 CD8 beta Protein, Human, Recombinant (hFc)

LYT3,CD8 β,CD8b...

Human HEK293 Cells
CD8 beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44 kDa and the accession number is P10966-1.
TMPY-05364 CD8 alpha Protein, Human, Recombinant (hFc)

Leu-2,p32 186910,p32,CD8 α,CD...

Human HEK293 Cells
CD8 alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.3 kDa and the accession number is P01732-1.
TMPY-05134 CD8 alpha Protein, Mouse, Recombinant (His), Biotinylated

Lyt-2,Ly-35,Ly-B,CD8a molecule,Ly-2,BB1543...

Mouse HEK293 Cells
CD8 alpha Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is P01731.
TMPY-06274 CD8 alpha Protein, Human, Recombinant (His)

CD8 alpha,Leu-2,p32 186910,CD...

Human CHO Cells
CD8 alpha Protein, Human, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 19 kDa and the accession number is P01732-1.
TMPY-05046 CD8 alpha Protein, Mouse, Recombinant (hFc)

BB154331,Ly-B,Ly-2,CD8 α,Lyt-2,Ly-35,C...

Mouse HEK293 Cells
CD8 alpha Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.6 kDa and the accession number is P01731.
TMPY-02165 CD8 alpha Protein, Ferret, Recombinant (His)

CD8a molecule,CD8 α

Ferret HEK293 Cells
CD8 alpha Protein, Ferret, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.5 kDa and the accession number is I6LI23.
TMPY-06275 CD8 alpha Protein, Human, Recombinant (His), Biotinylated

MAL,CD8,CD8a molecule,Le...

Human CHO Cells
CD8 alpha Protein, Human, Recombinant (His), Biotinylated is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 19 kDa and the accession number is P01732-1.
TMPY-03913 CD8 alpha Protein, Rat, Recombinant (hFc)

CD8 α,CD8a molecule

Rat HEK293 Cells
CD8 alpha Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45 kDa and the accession number is P07725.
TMPY-01314 CD8 alpha Protein, Mouse, Recombinant (His)

Ly-35,CD8a molecule,BB154331,Ly-2,Ly-B,

Mouse HEK293 Cells
CD8 alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is P01731.
TMPY-06933 CD8 alpha Protein, Human, Recombinant (His & Avi), Biotinylated

p32 186910,MAL,CD8,Leu2,CD

Human HEK293 Cells
CD8 alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 20.87 kDa and the accession number is NP_001759.3.
TMPK-00123 CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated

Leu2,CD8 α/CD8A,MAL,Lyt-...

Human HEK293 Cells
CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I, favoring lipid raft partitioning of TCR, and inducing intracellular signaling. CD8 alpha is also found on dendritic cells and rat macrophages, but whether CD8 alpha enhances responses of a partner receptor, like TCR, to activate these cells is not known.

重组蛋白

CD8 beta Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-04925
Species: Human
Expression System: HEK293 Cells
CD8 beta Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-06256
Species: Cynomolgus
Expression System: HEK293 Cells
CD8 beta Protein, Human, Recombinant (His)
Cat.No: TMPJ-00092
Species: Human
Expression System: HEK293 Cells
CD8 beta Protein, Human, Recombinant
Cat.No: TMPY-02925
Species: Human
Expression System: HEK293 Cells
CD8 alpha Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-05350
Species: Cynomolgus
Expression System: HEK293 Cells
CD8 beta Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02703
Species: Human
Expression System: HEK293 Cells
CD8 alpha Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05364
Species: Human
Expression System: HEK293 Cells
CD8 alpha Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-05134
Species: Mouse
Expression System: HEK293 Cells
CD8 alpha Protein, Human, Recombinant (His)
Cat.No: TMPY-06274
Species: Human
Expression System: CHO Cells
CD8 alpha Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05046
Species: Mouse
Expression System: HEK293 Cells
CD8 alpha Protein, Ferret, Recombinant (His)
Cat.No: TMPY-02165
Species: Ferret
Expression System: HEK293 Cells
CD8 alpha Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-06275
Species: Human
Expression System: CHO Cells
CD8 alpha Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03913
Species: Rat
Expression System: HEK293 Cells
CD8 alpha Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01314
Species: Mouse
Expression System: HEK293 Cells
CD8 alpha Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06933
Species: Human
Expression System: HEK293 Cells
CD8 alpha Protein, Human, Recombinant (aa 22-182, His & Avi), Biotinylated
Cat.No: TMPK-00123
Species: Human
Expression System: HEK293 Cells
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